情绪调节作为老年人压力与炎症之间关联的保护因素
情绪调节作为老年人压力与炎症之间关联的保护因素
Emotion regulation as a protective factor in the association between stress and inflammation in older adults
——《健康心理学》第44卷第12期，2025年12月——
【摘要】情绪调节多样性和整体情绪调节能力显著调节了压力与白细胞介素-6之间的前瞻性关联。目的：识别在压力和衰老背景下促进健康的社会心理因素至关重要。情绪调节（ER）可能就是这样一种保护因素。本研究检验了三种形式的情绪调节——个体情绪调节策略的使用、情绪调节策略的多样性以及整体情绪调节能力——作为感知压力与老年人炎症之间前瞻性关联的调节因素。方法：162名60岁以上的成年人完成了基线测量，包括感知压力、单独测试的情绪调节策略（情境选择、情境修正、认知重评和情绪接受），并将这些策略组合成情绪调节多样性指标，以及整体情绪调节能力的测量。在基线和随访（平均6.8个月后）时评估了炎症标志物（C反应蛋白、白细胞介素-6和肿瘤坏死因子-α）。残差变化模型检验了情绪调节措施作为压力与炎症之间关联的调节因素，并调整了基线炎症、人口统计学和健康协变量。分析对每种情绪调节形式的多重炎症结果进行了校正。结果：没有一种情绪调节策略能够调节压力与炎症之间的前瞻性关联（p>0.48）。情绪调节多样性和整体情绪调节能力分别显著调节了压力与白细胞介素-6（B=-0.13，调整后p=0.047）和C反应蛋白（B=0.14，调整后p=0.019）之间的前瞻性关联。较高的情绪调节多样性和较低的整体情绪调节能力缺陷具有保护作用，并减弱了压力与炎症之间的关联。结论：经历较高压力的老年人如果采用多种情绪调节策略并具有较高的整体情绪调节能力，则其白细胞介素-6和C反应蛋白水平较低，但其他标志物水平没有显著差异。初步结果表明，除个体策略之外的其他情绪调节方法可能在压力背景下促进健康的免疫衰老。
【关键词】心理神经免疫学，衰老，情感免疫学，情绪调节多样性
[Abstract] ER diversity and global ER ability significantly moderated the prospective association between stress and interleukin-6. Objective: Identifying psychosocial factors that promote health in the context of stress and aging is needed. Emotion regulation (ER) may be one such protective factor. The current study tested three forms of ER—use of individual ER strategies, diversity of ER strategies, and global ER ability—as moderators of the prospective association between perceived stress and inflammation in older adults. Method: Adults (N = 162) aged 60+ completed baseline measures of perceived stress, ER strategies (situation selection, situation modification, reappraisal, and emotional acceptance) tested individually, and combined into an ER diversity metric, and a measure of global ER ability. Inflammatory markers (C-reactive protein, interleukin-6, and tumor necrosis factor-α) were assessed at baseline and follow-up (average 6.8 months later). Residualized change models tested ER measures as moderators of the association between stress and inflammation, adjusting for baseline inflammation and demographic and health covariates. Analyses were corrected for testing multiple inflammatory outcomes per form of ER. Results: No one ER strategy moderated the prospective association between stress and inflammation (ps>.48). ER diversity and global ER ability significantly moderated the prospective association between stress and interleukin-6 (B=?.13, padjusted= .047) and C-reactive protein (B= .14, padjusted= .019), respectively. Higher ER diversity and lower deficit in global ER ability were protective and attenuated stress–inflammation associations. Conclusions: Older adults experiencing higher stress who employ a diversity of ER strategies and have higher global ER ability had lower levels of interleukin-6 and C-reactive protein, respectively, but not of other markers. Initial results suggest ER approaches other than individual strategies may promote healthy immune aging in the context of stress.
[Key words] psychoneuroimmunology, aging, affective immunology, emotion regulation diversity
论文原文：Rebecca G. Reed (2025). Emotion regulation as a protective factor in the association between stress and inflammation in older adults. Health Psychology, Volume 44, Issue 12, Pages 1105–1115. December 2025.
https://doi.org/10.1037/hea0001530
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